| Tatiana Maslany | Sarah Manning (and Clones) [DHR] | Corinna Riegner |
| Jordan Gavaris | Felix „Fee“ Dawkins [DHR] | Tobias Diakow |
| Dylan Bruce | Paul Dierden [DHR] | Rainer Fritzsche |
| Kevin Hanchard | Detective Arthur „Art“ Bell [DHR] | Fabian Körner |
| Michael Mando | Victor „Vic“ [DHR] | Daniel Sellier |
| Maria Doyle Kennedy | Siobhan „Mrs. S.“ Sandler [DHR] | Kerstin Fischer |
| Évelyne Brochu | Delphine Cormier [DNR] | Nora Jokhosha |
| Raj [DNR] | Lars Walther |
| Terra Hazelton | Sarah Stubbs [NR] | Ela Paul |
| Michelle Arvizu | La Camarera [ENR] | Claudia Dalchow |
| diverse [ENR] | Susann Sinnemann |
| Dr. Henry Bosch | Simon Böer |
