| Karin Thaler | Oberärztin Dr. Ulrike Kühn [DHR] | |
| Juliane Gibbins | Edda Bernstein [DHR] | |
| Stephen Dürr | Konrad Krause [DHR] | |
| Olaf Rauschenbach | Florian [DHR] | |
| Patrick Joswig | Fritz Müller [HR] | |
| Verena Zimmermann | Lisa Baumann [HR] | |
| Julia Haacke | Sabine Schulte [HR] | |
| Michael Trischan | Lehmann (Alle für einen) [EHR] | |
| Luka Omoto | Sarah Müller [EHR] | |
| Sonja Stein | Sylvie [EHR] | |
| Mathias Junge | Anästhesist [NR] | |
| Sandra Quadflieg | Krankenschwester [NR] | |
| Jörg Witte | Roman Winther [NR] | |
| Alexander Haugg | Imbißverkäufer Johny [NR] | |
| Rolf Kanies | Hiawatha [NR] | |
| Christof Wackernagel | Herr Tögel [NR] | |
| Heinrich Cuipers | Lintsch [NR] | |
| Claudia Kühn | Episodenrolle [NR] | |
| Franziska Lippert | Roula [NR] | |
| Martin May | Kurt Kaven [NR] | |
| Uwe Zerbe | Stahnke [NR] | |
| Frida Caroline Bruhn | Episodenhauptrolle [NR] | |
| Oliver Franck | Hagen Keller (Episoden-HR) [NR] | |
| Christine Kutschera | Patientin [ENR] | |
| Anette Hellwig | Episodenrolle | |
